Designed with plane or car travel in mind but useful for anyone sitting for long periods of time. The 5 zones of medical grade compression range from light (10-15 mmHg) to moderate (15-20 mmHg) to improve circulation and prevent discomfort during extended immobility. For the best fit, it is important that you use the size chart before ordering. Targeted conditions: Circulation, Deep Vein Thrombosis, leg cramps and fatigue, achy legs and feet Medical grade compression made on FDA registered machinery Included in all Socks with Purpose® Micro-nylon treated with silver-ion technology to keep dry and prevent odor Seamless construction and left/right design for 360-degree blister protection Y-Gore heel to prevent the sock from slipping down into your shoe Care Instructions: Wash gentle on cold. Tumble dry on low heat. No bleach or fabric softener.